Center for Functional Data Analysis

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The goal is to establish a Center of functional data analysis with a particular focus on online prediction of clinical adverse events. The types of data focused will be continuously collected data such as ECG, EEG, optical imaging data, longitudinal biomarkers, vital sign data, and data collected through wearable devices or other online monitors.

The overarching aim is to use patient-level, continuous data for feature extraction and a) to train prediction models; b) to validate the results prospectively; and c) to design timely interventions to prevent acute and subacute complications of disease. We will collaborate broadly with investigators in the University of Pennsylvania Perelman School of Medicine to analyze these types of data and to develop methodology to meet the new challenges.

Center Objectives

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  • Feature extraction from functional data and online prediction of adverse clinical events.
  • One project is to analyze telemetry data that builds on our current R01 work in 12-lead electrocardiogram.
  • Online prediction methodology has broad applications across Penn medicine. 

CFDA Board of Directors

Wensheng Guo, PhD Wensheng Guo, PhD Professor of Biostatistics in Biostatistics and Epidemiology Email Learn More Rajat Deo, MD, MTR Rajat Deo, MD, MTR Associate Professor of Medicine (Cardiovascular Medicine) at the Hospital of the University of Pennsylvania Email Wei (Peter) Yang, PhD Wei (Peter) Yang, PhD Associate Professor of Biostatistics Email Learn More